Stay weight wise
Excess pounds boost cancer risk, a study in The Lancet shows. Build an exercise
habit now to head off trouble: The American Cancer Society (ACS) recommends
aiming for 30 minutes of activity five days a week.

When you hit your 45th birthday, make sure you're also doing 45 minutes of
strength training twice weekly to minimize metabolic slowdown. "Beginning in our mid-
40s, we lose up to a third of a pound of muscle a year and gain it back as fat, and
fat burns fewer calories than muscle," says Miriam Nelson, Ph.D., director of Tufts
University John Hancock Center for Physical Activity and Nutrition in Boston.






Nibble a bit of chocolate
As if you need an excuse! Researchers have discovered a compound in dark
chocolate that fights fast-growing cancers such as colorectal cancer. "It requires the
activity of an enzyme called kinase, which causes cancerous cells to die but leaves
normal cells alone," says Richard Pestell, M.D., director of the Kimmel Cancer
Center at Thomas Jefferson University in Philadelphia. The finding could even lead
to adding chocolate to current cancer treatments.







Practice peace
Say ahhh! High levels of the stress hormone cortisol may inhibit a key gene from
suppressing tumor growth, findings in the journal Genes, Chromosomes & Cancer
suggest. Tame tension with this formula from the University of Pittsburgh Medical
Center Healthy Lifestyle Program:
Take deep belly breaths. You slow and elongate brain waves, bringing on calm.
Watch your favorite comedy. Enjoying a good laugh activates the areas of the brain
that govern humor, in turn suppressing the brain's stress regions.
Adopt an uplifting mantra. Try "I love my life!" and repeat it when you're happy. You
will train your mind to associate the phrase with being content. Then when you're on
edge, chant your mantra and you'll immediately feel at ease.




Bake, don't burn
Grilling beef, poultry and fish until it's charred to a crisp can turn amino acids and
other substances in the meat into heterocyclic amines (HCAs), compounds that
have been linked to cancer. "HCAs are 10 times more potent than most other
environmental carcinogens," says Kenneth Turteltaub, Ph.D., a toxicologist at
Lawrence Livermore National Laboratory in California. Try these cookin'-good tips!

Marinate meat before grilling. Soaking chicken breasts in a mixture of cider vinegar,
olive oil, lemon juice and spices reduced HCA formation by 92 to 99 percent, notes
a study published in Food and Chemical Toxicology. "Marinating creates a barrier
between the hot surface and meat, enough to lower the temperature and prevent
HCAs from forming," Turteltaub says.
Keep the grill temp below 325 degrees, the point at which HCAs begin to form.
Grill meat or fish in punctured aluminum foil to protect against flare-ups. When fat
drips on the hot coals, it forms HCAs, plus other carcinogens called polycyclic
aromatic hydrocarbons that rise with the smoke.
Microwave beef burgers for one to three minutes before browning; doing so reduces
HCA production by 95 percent, according to a study in Food and Chemical
Toxicology. Prior to grilling, discard the juices, which contain the building blocks of
HCAs.
Flip burgers often—about once a minute. This action keeps meat juices from getting
too hot and activating HCA formation.





Avoid needless tests
Those full-body computed tomography scans you sometimes see at the mall are
bad news: CT scans deliver a dose of radiation 50 to 200 times that of a
conventional X-ray. A study from Massachusetts General Hospital in Boston found
that for every 1,000 patients screened, an average of 908 would have at least one
false-positive result, requiring further testing.

Stick to shopping when at the mall, and if your doc orders a nonemergency CT scan
(say, to investigate headaches), ask if a radiation-free ultrasound or an MRI can be
used instead, says Devra Davis, Ph.D., director of the Center for Environmental
Oncology at the Uni­versity of Pittsburgh Cancer Institute.







Steal these secrets
Cancer rates in some countries are significantly lower than in the United States, and
many experts attribute this to the lifestyles of people in these areas. Adopt these
disease-fighting behaviors from afar:

Spice things up. In India, where breast cancer rates are about five times lower than
in the United States, people cook with an abundance of cancer-fighting spices such
as cumin, ginger and turmeric.
Go for whole grains. Finland natives are known for eating loads of dark rye and
other whole-grain breads, which likely contributes to their low colorectal cancer
rates.
Kick butts. West Africans smoke much less than Americans, which may in part
explain why their rates of esophageal cancer are about 60 times lower than ours.







Take a shot at HPV
More women may soon benefit from Gardasil, a vaccine that protects against the
two strains of human papillomavirus that cause 70 percent of cervical cancer cases.
The FDA decided in March to give priority review to the potential use of the vaccine,
currently approved for women ages 9 to 26, for women ages 27 to 45.

"Older women have likely already been exposed to several HPV strains, but the
vaccine could protect against other strains they haven't yet come in contact with,"
explains Debbie Saslow, Ph.D., director of breast and gynecological cancers for the
ACS.









Breathe easily
Radon is a leading cause of lung cancer among nonsmokers. The odorless radio-
active gas is linked to up to 22,000 cancer deaths annually, according to the
National Cancer Institute (NCI).
It is released during the decay of uranium, an element found in many soils, and can
seep into your house. "When inhaled, radon can break down cell DNA and lead to
cancer," Davis explains. To test your home, look for a do-it-yourself kit at a home-
improvement store.












Cut back on coffee
The number of esophageal cancer cases has jumped 300 percent in the past 20
years, the U.S. Agency for Healthcare Research and Quality reports. A primary
cause: chronic reflux, which bathes the throat in stomach acids that can erode
tissue.

To put out the flames, avoid top triggers like caffeine and alcohol. "They relax the
sphincter muscle at the bottom of the esophagus, allowing stomach juices to splash
up," says Yvonne Romero, M.D., assistant professor of medicine at the Mayo Clinic
College of Medicine in Rochester, Minn.











Ponder the Pill carefully
Research on the link between birth control pills and cancer reveals the
contraceptive can be a mixed blessing. On the one hand, women who took the Pill
for 15 years cut their risk for ovarian and endometrial cancer by more than half,
notes a study from the University of Oxford in England. Experts say that by
suppressing ovulation, the Pill reduces the cell damage that can lead to tumors.

On the other hand, Pill takers may have a slightly elevated risk for breast and
cervical cancer. So what's the bottom line? "For most healthy women who don't
smoke, the benefits of the Pill far exceed the risks," says Polly Marchbanks, Ph.D.,
an epidemiologist at the Centers for Disease Control in Atlanta. The cancer risks
that do exist begin to decline once you stop taking oral contraceptives. Regardless,
consult your gynecologist to learn what's best for you.









Be sunscreen-savvy
Melanoma rates among young women jumped 50 percent between 1980 and 2004,
the Journal of Investigative Dermatology reports.

Apply sunscreen properly: Put on the amount that would fill a shot glass 30 minutes
before heading outdoors, then reapply every two hours or after swimming or major
sweating. Also, look for broad-spectrum coverage and UVA-filtering ingredients
such as Mexoryl, avobenzone and zinc oxide.











Ask about daily aspirin
It's not only for heart disease: One a day reduced estrogen-receptor-positive breast
cancer risk by 16 percent, NCI research finds. "Aspirin may block cyclooxygenase,
an enzyme that could disrupt cancer development, in part by reducing estrogen
levels," says lead researcher Gretchen Gierach, Ph.D. More research is needed,
though; long-term aspirin use can cause ulcers.












Beware of false promises
At least 25 companies have misleadingly marketed products containing ingredients
like shark cartilage, exotic mushrooms and wild yam as cancer treatments or
preventives, prompting the FDA to issue a warning this summer. One supplement,
CancerGene, claimed to "help switch on all three genes that inhibit cancer." "These
products aren't proven safe or effective," says FDA spokeswoman Rita Chappelle in
Rockville, Md.
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