Green Tea May Give Full Body Protection

AICR's most recent international conference unveiled new findings on the cancer-fighting
power of green tea. Research now shows that a major component in green tea may
short-circuit the cancer process more extensively than scientists had realized.
From American Institute for Cancer Research

Green tea is one of the substances in Asian diets that may provide potent protection against
cancer, according to research studies. Even though green tea has yet to catch on in the U.S.
and other Western countries as a daily drink of choice, a growing number of laboratories are
exploring green tea's cancer-fighting effects on a cellular level.

One scientist who has spent the past several years studying a particular phytochemical found
in green tea is Dr. Thomas A. Gasiewicz, Professor and Chairman of the Department of
Environmental Medicine at the University of Rochester Medical Center.

Green Tea Short-Circuits the Cancer Process

"A unique quirk of biochemistry allows green tea's protective effects to extend to many
different kinds of cells," says Dr. Gasiewicz. "In fact, one of the active green tea substances -
called EGCG (epigallocatechin-3-gallate) - seems to target one protein that is common
throughout our bodies. And it does so with a degree of precision that cancer drugs still aren't
able to match."

This protein is called HSP90, and it is present at high levels in many cancer cells. Scientists
believe that, in some circumstances, HSP90 helps to trigger the series of changes in cells
that eventually lead to cancer.

However, when green tea's EGCG binds to this protein, it helps to prevent these changes
from happening. "EGCG targets HSP90, binds directly to it, and keeps it from passing on
signals that can start the cancer process," Dr. Gasiewicz explains. "As a result, potentially
harmful genes are less likely to get turned on." This is important, because HSP90 is present
in all of our cells.

Solving a Diet-Cancer Mystery

"If further research confirms that EGCG's ability to bind to such a basic protein enables it to
provide protection throughout our bodies, it explains a scientific mystery," says Dr. Gasiewicz.
"Studies that track the diets of human subjects over several years - particularly studies
conducted in Asia, where green tea consumption is common - have associated regular usage
of green tea with lower risk for cancers that are vastly different from one another."

Asian data links green tea to reduced risk for breast, prostate, bladder, colon, stomach,
pancreatic and esophageal cancers. This new finding shows that EGCG may be effective
against an important "common denominator" for many different cancers, at the very start of
the cancer process.

EGCG Does What Cancer Drugs Can't Yet Do

Green tea's EGCG acts with a natural precision that scientists have not yet been able to
duplicate in a drug. Because cancer cells tend to have higher levels of HSP90 than healthy
cells, pharmaceutical researchers have tried to develop a drug that keeps HSP90 from
sending the biochemical signals that can trigger cancer. But nothing seems to work as
perfectly as green tea's EGCG.

Unlike black tea or oolong, regular green tea leaves are baked or steamed before they can
oxidize, so their EGCG level remains high. Regular green tea has more EGCG than
decaffeinated green tea, although you can drink more cups of the decaffeinated kind to
compensate. As for caffeine alone, regular green tea has 30 mg per cup compared to 43 mg
in black tea and 135-179 mg per cup of caffeinated coffee.

Warm Up to Green Tea's Benefits

An AICR telephone survey showed that Americans rarely drink green tea, even though it is
higher in beneficial phytochemicals and lower in caffeine than black tea, coffee, or colas.
Even those who said they drank it every day drank far smaller amounts than Asian

Japanese and Chinese people drink an average of 3-4 cups of green tea daily, per person.
According to the AICR survey, fewer than 1 percent of Americans are drinking the equivalent
amount (roughly 2-3 American-size cups) of green tea. Nearly 7 in 10 Americans (68 percent)
said they drank green tea rarely or never. By comparison, a recent scientific study reported
that only 8 percent of Japanese people say they drink green tea rarely or never.

"Drinking some green tea every day is a good way to add to the cancer protection we get
from eating a diet high in plant foods and low in fat and salt," says Dr. Ritva Butrum, Senior
Science Advisor at AICR.

Try different kinds of green tea to find which ones you like best. More than 40 types of
Chinese green tea and eight different types of Japanese green teas can be found either at
specialty stores or through web sites. Create your own special brew with lemon, honey or